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KMID : 0984920160180010085
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Journal of Skin Barrier Research
2016 Volume.18 No. 1 p.85 ~ p.85
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The Clinical Assessment of Cosmetic Products for The Management of Atopic Dermatitis
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Hong Seung-Phil
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Abstract
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Atopic dermatitis (AD) is a chronic skin disease featured by defects in the skin barrier function and cutaneous inflammation, in which transepidermal water loss is increased and the ability of the stratum corneum to hold water is impaired. The diminished barrier function seen in patients with AD contributes to their striking susceptibility to colonization and infection of pathogens and an increased penetration of allergens. Because it is known that moisturizers play an important role in improving skin barrier and preventing skin inflammation, the use of moisturizers is strongly emphasized in the treatment of AD. In this situation, clinicians have to choice and recommend a proper moisturizer for their patient among many products in the market.
Accordingly, the suitability of assessment methods in the clinical study with cosmetic products is importance issue to accept the moisturizer as a therapeutic agent in the treatment of AD. This section will review representative clinical reports with cosmetic products (moisturizers) in patients with AD and then discuss about the proper clinical assessment methods.
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KEYWORD
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